Listen again · In Conversation
Can New Ebola Vaccines Help Control the Outbreak?
· 6:38 · With Maya, Grace, and Alex
Our station shares news and stories in clear English to help us understand the world. I’m Maya. Grace covers health and medicine, and Alex is a journalist. Thanks for listening.
Transcript
Vocabulary in this episode
- ongoing trial
The immediate news is that two vaccine candidates may join an ongoing trial in the Democratic Republic of the Congo, or DRC.
A study that is already continuing is an ongoing trial.
- licensed
WHO says there is no vaccine licensed for Bundibugyo virus disease.
Here, licensed means officially approved for use.
- licensed
Ervebo is licensed for Ebola virus disease, but WHO says evidence is not enough to know whether it protects people against Bundibugyo virus.
Here, licensed means officially approved for use against this disease.
- widespread
WHO described transmission as widespread.
The virus was spreading across a large area.
- widespread
That is a meaningful step in the search for protection, while the outbreak remains widespread and the candidates are still unproven.
The outbreak is still affecting a large area.
- convened
Expert groups convened by WHO recommended adding them to the Tumaini trial.
The groups were brought together for a meeting by WHO.
- ring vaccination
It uses ring vaccination, which means offering vaccination to people who had contact with a confirmed case.
This means offering vaccines to people around a confirmed case, to help stop the virus spreading.
- ring vaccination
WHO says it builds on ring vaccination used during the West Africa Ebola outbreak about a decade ago.
This is vaccination offered to people who had contact with a confirmed case.
- exposed to
Contacts are people who may have been exposed to someone with the disease.
They may have come into contact with the virus through a sick person.
- in close consultation with
WHO says research should be conducted in close consultation with affected communities.
Researchers should discuss the work carefully with the communities affected.
- builds on
WHO says it builds on ring vaccination used during the West Africa Ebola outbreak about a decade ago.
The current work uses an earlier approach as a starting point.
- contact tracing
WHO says the response still relies on surveillance, rapid testing, contact tracing, isolation and care, infection prevention, community engagement, and safe burials.
This means finding people who had contact with someone who has the disease.
- weigh
Grace, how should listeners weigh the promise of vaccines against those measures?
Here, weigh means consider and compare the value of vaccines and the other measures.
- unproven
That is a meaningful step in the search for protection, while the outbreak remains widespread and the candidates are still unproven.
The candidates have not yet been shown to work.
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Sources
- BBC NewsThe NHS is relying more on charities - and that might be creating problems for patients - BBC News
- AfricanewsWHO approves clinical trials on two new Ebola vaccines
- Le MondeClient Challenge
- MedPage TodayA Pediatrician, a Pastor, and a Paralympian Just Did Wonders for Kids’ Mental Health | MedPage Today
- STATHealth care as a top midterm issue: Why doctors, scientists did so well | STAT
- RechercheIn the WHO outbreak account, the response relies on surveillance, rapid testing, contact tracing, isolation and care, infection prevention, community engagement and safe burials; WHO Director-General Tedros said vaccines alone will not end the outbreak.
- Ebola outbreak - DRC 2026
- Experts convened by WHO advise on candidate treatments and vaccines for Ebola disease caused by Bundibugyo virus
- Ebola disease caused by Bundibugyo virus - Democratic Republic of the Congo
- WHO and Africa CDC welcome the allocation of Ebola vaccines to the Democratic Republic of the Congo
- Ongoing outbreak in the Democratic Republic of the Congo | WHO | Regional Office for Africa
- RechercheWHO says no vaccine is licensed specifically for Bundibugyo virus disease. Ervebo is licensed for Ebola virus disease caused by Ebola virus, and available evidence is insufficient to establish whether it protects humans against Bundibugyo virus.
- WHO Rapid Risk Assessment-Ebola disease caused by Bundibugyo virus, Democratic Republic of the Congo v4
- Ebola disease caused by Bundibugyo virus, Democratic Republic of the Congo & Uganda
- Ebola disease
- Client Challenge
- La OMS confía en dos vacunas “prometedoras” contra el ébola Bundibugyo que podrán probarse con personas en unos meses | Planeta Futuro | EL PAÍS
- Ring vaccination - Wikipedia
- rVSV-ZEBOV vaccine - Wikipedia
- RechercheAs of 11 October, the DRC had reported 9,066 confirmed Bundibugyo virus disease cases and 4,381 confirmed deaths across 65 health zones in seven provinces; WHO said transmission remained widespread.
- Second meeting of the IHR Emergency Committee on the epidemic of Ebola Bundibugyo virus disease in the Democratic Republic of the Congo – Meeting report
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- WHO approves clinical trials on two new Ebola vaccines | Africanews
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- Ebola disease caused by Bundibugyo virus - Democratic Republic of the Congo
