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Commentary

New blood test signal may help spot ovarian cancer earlier

· 2:40 · A signal before cancer · With Nora

Today, a study asks whether a blood test could spot a warning sign before ovarian cancer becomes invasive.

Transcript

Vocabulary in this episode
invasive

Today, a study asks whether a blood test could spot a warning sign before ovarian cancer becomes invasive.

Here, it means cancer that has grown into nearby tissue.

invasive

It involves microscopic changes, not an invasive cancer.

Here, it describes cancer that has grown into nearby tissue.

invasive

This research instead looked for molecular warning signs before invasive cancer develops.

Here, it means cancer that grows into nearby tissue.

fallopian tubes

Ovarian cancer can begin with microscopic changes in the lining of the fallopian tubes.

These are the tubes that carry eggs from the ovaries toward the womb.

lining

Ovarian cancer can begin with microscopic changes in the lining of the fallopian tubes.

It is the thin layer of tissue on the inside of the tubes.

precursor condition

Researchers looked for a signal linked to this precursor condition, rather than trying to find a small tumor.

A condition that may come before a later disease.

elevated levels

Tu-Stroma is an RNA molecule that the study found at elevated levels in the blood of women with STIC.

The amount was higher than usual.

detected

In the study, measuring Tu-Stroma detected STIC in 92.3 percent of affected women.

It found or identified STIC in those women.

identified

It also correctly identified 98.2 percent of healthy women.

It correctly recognized which women were healthy.

early detection

The idea represents a different way to think about early detection.

Finding a disease or warning sign at an early stage.

early detection

The study found a possible approach to early detection, and co-author Esha Madan said it could eventually provide information relevant to preventive-surgery decisions.

Here, it means finding a disease or warning sign early.

set out to

Study leader Rajan Gogna said that was the question the researchers set out to ask.

They began their work with the aim of asking that question.

genetic risk factors

Many women with genetic risk factors face difficult decisions about preventive surgery.

Inherited traits that may make someone more likely to develop a disease.

precancerous

Researchers may have found a measurable signal linked to STIC, a precancerous condition.

It describes a condition that may develop into cancer but is not cancer itself.

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